端粒介紹：諾貝爾醫學獎的啟示
TELOMERE
How Chromosomes Are Protected By Telomeres And The Enzyme Telomerase.
LIFE CLOCK 生命時鐘
青春流失的速度，比我們想得更快。熬夜加班、壓力焦慮、菸酒糖過量，這些生活習慣正悄悄侵蝕體內的「生命時鐘」。這個時鐘，叫做 端粒 Telomere，它藏在細胞最深處，決定著我們老得有多快、年輕能撐多久。
Youth Fades Faster Than We Think
The speed at which youth fades is faster than we imagine. Late nights, overwork, stress, anxiety, smoking, drinking, and sugar —these habits quietly wear down the vitality within us.
The Silent Keeper: Telomere
Deep inside our cells lies the Telomere — the silent keeper of our biological clock. It determines how quickly we age and how long we can hold on to youth.
COUNTDOWN 倒數計時中
細胞的每次的修復與分裂， 染色體上的端粒就會變短 50-100 鹼基對。 隨著年齡增長，端粒降低至 5000 鹼基對 後， 就停止生長，進入衰老期。
The Aging Clock Within Our Cells
With each cellular repair and division, the telomeres on our chromosomes shorten by 50 to 100 base pairs. As we age, when telomeres shrink to around 5,000 base pairs, cells stop dividing and enter a state of senescence.
端粒與端粒酶
守護染色體的青春防線
諾貝爾醫學獎肯定研究
2009
諾貝爾醫學獎肯定研究
三位科學家實驗發現 端粒酶（Telomerase） 可以修復端粒、維持染色體端粒長度、 穩定染色體 DNA 結構，更獲得諾貝爾獎肯定。 改寫我們對健康維持、青春美麗的認知。
Nobel Prize Recognizes Telomerase Discovery
In 2009, three scientists discovered that the enzyme telomerase can repair telomeres, maintain the length of chromosome ends, and stabilize the DNA structure. This groundbreaking research was recognized with the Nobel Prize in Physiology or Medicine, reshaping our understanding of health maintenance, youthfulness, and beauty.
Nobel Prize Recognizes Telomerase Discovery
In 2009, three scientists discovered that the enzyme telomerase can repair telomeres, maintain the length of chromosome ends, and stabilize the DNA structure. This groundbreaking research was recognized with the Nobel Prize in Physiology or Medicine, reshaping our understanding of health maintenance, youthfulness, and beauty.
Elizabeth H. Blackburn
美澳分子生物學家
Elizabeth H. Blackburn
美澳分子生物學家
Carol W. Greider
美國分子生物學家
Carol W. Greider
美國分子生物學家
Jack W. Szostak
美國生物學家
Jack W. Szostak
美國生物學家
諾貝爾得獎對端粒酶研究顯示
Association between telomere length and mortality in elderly. The Lancet (2003)
01
端粒越短
老化風險越高
端粒每縮短 1Kb，死亡風險增加 23%。
Accelerated telomere shortening in response to life stress. Proceedings of the National Academy of Sciences (PNAS) (2004)
02
端粒長度
和外貌年齡有關
端粒較長者，看起來比實際年齡年輕 5～8 歲。
Stress, telomeres, and aging: An update. Nature Reviews Neuroscience (2012)
03
壓力與習慣
會加速端粒縮短
長期心理壓力會加速端粒縮短，影響免疫細胞壽命。
Telomerase reactivation reverses tissue degeneration in aged mice. Nature (2011)
04
端粒酶改善老化、
延長壽命
小鼠實驗證實：啟動端粒酶可逆轉器官老化。
表裡如一，不留痕跡
端粒介紹：諾貝爾醫學獎的啟示
TELOMERE
Whether it’s through stunning designs or seamless user experiences, I’m dedicated to delivering work that inspires and resonates.
LIFE CLOCK 生命時鐘
青春流失的速度，比我們想得更快。熬夜加班、壓力焦慮、菸酒糖過量，這些生活習慣正悄悄侵蝕體內的「生命時鐘」。這個時鐘，叫做 端粒 Telomere，它藏在細胞最深處，決定著我們老得有多快、年輕能撐多久。
Youth Fades Faster Than We Think
The speed at which youth fades is faster than we imagine. Late nights, overwork, stress, anxiety, smoking, drinking, and sugar —these habits quietly wear down the vitality within us.
The Silent Keeper: Telomere
Deep inside our cells lies the Telomere — the silent keeper of our biological clock. It determines how quickly we age and how long we can hold on to youth.
COUNTDOWN 倒數計時中
細胞的每次的修復與分裂， 染色體上的端粒就會變短 50-100 鹼基對。 隨著年齡增長，端粒降低至 5000 鹼基對 後， 就停止生長，進入衰老期。
The Aging Clock Within Our Cells
With each cellular repair and division, the telomeres on our chromosomes shorten by 50 to 100 base pairs. As we age, when telomeres shrink to around 5,000 base pairs, cells stop dividing and enter a state of senescence.
端粒與端粒酶
守護染色體
的青春防線
諾貝爾醫學獎肯定研究
2009
諾貝爾醫學獎
肯定研究
三位科學家實驗發現 端粒酶（Telomerase） 可以修復端粒、維持染色體端粒長度、 穩定染色體 DNA 結構，更獲得諾貝爾獎肯定。 改寫我們對健康維持、青春美麗的認知。
Nobel Prize Recognizes Telomerase Discovery
In 2009, three scientists discovered that the enzyme telomerase can repair telomeres, maintain the length of chromosome ends, and stabilize the DNA structure. This groundbreaking research was recognized with the Nobel Prize in Physiology or Medicine, reshaping our understanding of health maintenance, youthfulness, and beauty.
Elizabeth H. Blackburn
美澳分子生物學家
Carol W. Greider
美國分子生物學家
Jack W. Szostak
美國生物學家
諾貝爾得獎對端粒酶研究顯示
Association between telomere length and mortality in elderly. The Lancet (2003)
01
端粒越短
老化風險越高
端粒每縮短 1Kb，死亡風險增加 23%。
Accelerated telomere shortening in response to life stress. Proceedings of the National Academy of Sciences (PNAS) (2004)
02
端粒長度
和外貌年齡有關
端粒較長者，看起來比實際年齡年輕 5～8 歲。
Stress, telomeres, and aging: An update. Nature Reviews Neuroscience (2012)
03
壓力與習慣
會加速端粒縮短
長期心理壓力會加速端粒縮短，影響免疫細胞壽命。
Telomerase reactivation reverses tissue degeneration in aged mice. Nature (2011)
04
端粒酶改善老化、
延長壽命
小鼠實驗證實：啟動端粒酶可逆轉器官老化。
表裡如一
不留痕跡
端粒介紹：諾貝爾醫學獎的啟示
TELOMERE
Whether it’s through stunning designs or seamless user experiences, I’m dedicated to delivering work that inspires and resonates.
LIFE CLOCK 生命時鐘
青春流失的速度，比我們想得更快。熬夜加班、壓力焦慮、菸酒糖過量，這些生活習慣正悄悄侵蝕體內的「生命時鐘」。這個時鐘，叫做 端粒 Telomere，它藏在細胞最深處，決定著我們老得有多快、年輕能撐多久。
Youth Fades Faster Than We Think
The speed at which youth fades is faster than we imagine. Late nights, overwork, stress, anxiety, smoking, drinking, and sugar —these habits quietly wear down the vitality within us.
The Silent Keeper: Telomere
Deep inside our cells lies the Telomere — the silent keeper of our biological clock. It determines how quickly we age and how long we can hold on to youth.
COUNTDOWN 倒數計時中
細胞的每次的修復與分裂， 染色體上的端粒就會變短 50-100 鹼基對。 隨著年齡增長，端粒降低至 5000 鹼基對 後， 就停止生長，進入衰老期。
The Aging Clock Within Our Cells
With each cellular repair and division, the telomeres on our chromosomes shorten by 50 to 100 base pairs. As we age, when telomeres shrink to around 5,000 base pairs, cells stop dividing and enter a state of senescence.
端粒與端粒酶
守護染色體
的青春防線
諾貝爾醫學獎肯定研究
2009
諾貝爾醫學獎肯定研究
三位科學家實驗發現 端粒酶（Telomerase） 可以修復端粒、維持染色體端粒長度、 穩定染色體 DNA 結構，更獲得諾貝爾獎肯定。 改寫我們對健康維持、青春美麗的認知。
Nobel Prize Recognizes Telomerase Discovery
In 2009, three scientists discovered that the enzyme telomerase can repair telomeres, maintain the length of chromosome ends, and stabilize the DNA structure. This groundbreaking research was recognized with the Nobel Prize in Physiology or Medicine, reshaping our understanding of health maintenance, youthfulness, and beauty.
Elizabeth H. Blackburn
美澳分子生物學家
Carol W. Greider
美國分子生物學家
Jack W. Szostak
美國生物學家
諾貝爾得獎對端粒酶研究顯示
Association between telomere length and mortality in elderly. The Lancet (2003)
01
端粒越短
老化風險越高
端粒每縮短 1Kb，死亡風險增加 23%。
Accelerated telomere shortening in response to life stress. Proceedings of the National Academy of Sciences (PNAS) (2004)
02
端粒長度
和外貌年齡有關
端粒較長者，看起來比實際年齡年輕 5～8 歲。
Stress, telomeres, and aging: An update. Nature Reviews Neuroscience (2012)
03
壓力與習慣
會加速端粒縮短
長期心理壓力會加速端粒縮短，影響免疫細胞壽命。
Telomerase reactivation reverses tissue degeneration in aged mice. Nature (2011)
04
端粒酶改善老化、
延長壽命
小鼠實驗證實：啟動端粒酶可逆轉器官老化。